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2021 Feb 4;11(2):217

IGF-1 LR3 works by mimicking the actions of insulin, interacting with cells to stimulate growth and energy use

(7) Another study, lasting 16 weeks, posited that Sermorelin might potentially result in up to a 107% rise in growth hormone levels and up to a 28% uptick in IGF-1 levels

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This distinction makes CJC 1295/Ipamorelin a safer, more physiological approach to GH optimization